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Approval of first RNA interference drug – why the excitement?

Phys.org - Fri 17 Aug 18

Small interfering RNA sounds like something from a science fiction novel rather than a revolutionary type of medicine. But this odd-sounding new drug offers a novel strategy for treating disease ...

First RNAi Therapy Approved by FDA

The Scientist - Fri 10 Aug 18

Alnylam's patisiran interferes with the production of a mutated protein present in people with hereditary transthyretin amyloidosis.

The first gene-silencing drug wins FDA approval

ScienceNews - Fri 10 Aug 18

The FDA just approved the first drug that works via RNA interference.

US approves first RNA interference drug

Chemistry World - Thu 16 Aug 18

Alnylam’s Onpattro (patisiran) can treat a rare hereditary disease by silencing a specific gene

Alnylam's gene silencing drug wins FDA approval

Reuters - Fri 10 Aug 18

Alnylam Pharmaceuticals Inc's drug for a rare hereditary disease won U.S. regulatory approval on Friday, becoming the first approved treatment from a new class of medicines that use gene silencing ...

Patisiran Wins Two Firsts With FDA Approval

MedPageToday - Fri 10 Aug 18

(MedPage Today) -- RNAi drug OK'd to treat polyneuropathy from hereditary transthyretin amyloidosis

Amid Giddiness Over First-Ever Gene-Silencing Drug’s Approval Is An Acknowledgment Of Its Limitations

Kaiser Health News - Tue 14 Aug 18

Right now, the RNAi drug is limited to cells that go through the liver, which is -- in relative terms -- easy to target. Getting the drug to other tissue, like the skin or brain, is more challenging. ...